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Human Resources

Research Programme 1: Protein-protein interactions (RP 1)


WP 1.1. Targeting enzymes involved in extracellular matrix degradation


WP 1.2. Targeting protein-protein interactions in leukemia


WP 1.3. Protein-protein interactions targeted by computational fragment-based design


WP 1.4. Targeting Ameloblastin, an intrinsically disordered protein from enamel matrix


WP 1.5. Development of insulin mimetics


WP 1.6. Targerting insulin storage forms in pancreatic secretory granules


WP 1.7. Targeting interactions of membrane receptors with other proteins and peptidomimetics


WP 1.8. Controlling specific protein-protein interactions using nanoparticles


WP 1.9. Targeting protein-protein interactions of host-virus interface


WP 1.10. Targeting interaction of HBV core, precore and X proteins with host cell machineries


WP 1.11. Development of compounds disrupting protein-protein interaction in influenza A polymerase


RP 2: Protein-membrane interactions

WP 2.1. Targeting and crossing complex cellular membranes


WP 2.2. Inhibition of intramembrane catalysis and protein-protein interactions for novel targeting of inflammatory and cancer pathologies


WP 2.3. Targeting host-virus interactions on membranes


RP 3: Protein-nucleic acid interactions

WP 3.1. Development of aptamers against oncogenic factors


WP 3.2. Development of functional DNA motifs that target HBV


WP 3.3. Development of anti-HBV compounds targeting STING protein


WP 3.4. Development of Nanoparticles for targeted gene editing


WP 3.5. Engineering of peptide scaffolds disrupting protein-nucleic acid interactions – a case of EST and HIF-1 transcription factors involved in cancer